Treatment: Oral Methylphenidate (Ritalin) Indication: Attention shortfall hyperactivity disorder (ADHD) Current attitude: Most commonly prescribe psychoactive drug for manipulation (Volkow, 2001) Study 1: Schachter, Howard M.; Pham, Ba; et al (2001) How efficacious and safe is short-acting methylphenidate for the word of attention shortage disorder in children and adolescents? This study was conducted to visit the need for a meta-analysis of studies done which had focused on short-acting methylphenidate compared with a placebo. The researchers include previous studies which met the fol economic crisising conditions: a placebo reserveled randomized attempt that winding short acting MP and participants corned 18 geezerhood or less at the take oer of the trial who had received any primary diagnosis of add that was do in a systematic and reproducible way. (Schacter, 2001) The 62 studies that were selected had some(prenominal) disfigures -- they were randomized trial s involving 2897 participants who had a primary diagnosis of ADD. all over 88% of participants were male and using two separate indices the trials exhibited let out quality. In addition, the interventions were conducted over a relatively short fix period -- no longer than 28 weeks. The results of the intervention were spread over by both teachers and parents but the possibility of publication gestate notion impacts the positive results achieved by these studies.

Even though the results were statistically significant, the aloofness of the placebo-controlled effect was not demonstrated past quatern weeks. This meta-analysis indicated that nigh studies had focused on the efficacy of stimulants relative to separate treatme! nts. truly few studies focused on the clinical usefulness of MP compared with placebo. The authors feel this was a very large flaw in the studies because in order to determine whether a drug is effective, on that point must be a control (placebo). Study 2: Nora D. Volkow, Gene-Jack Wang, et al (2001) Therapeutic Doses of oral... If you want to rent a full essay, order it on our website:
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